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Co-immunization with tandem repeat heterologous M2 extracellular proteins overcomes strain-specific protection of split vaccine against influenza A virus

Current influenza vaccines are less efficacious against antigenically different influenza A viruses. This study presents an approach to overcome strain-specific protection, using a strategy of co-immunization with seasonal H3N2 split vaccine and yeast-expressed soluble proteins of a tandem repeat co...

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Lee, Yu-Na, Kim, Min-Chul, Lee, Young-Tae, Kim, Yu-Jin, Lee, Jongsang, Kim, Cheol, Ha, Suk-Hoon, Kang, Sang-Moo
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560976/
https://ncbi.nlm.nih.gov/pubmed/26248203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2015.08.001
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