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Model reduction for stochastic CaMKII reaction kinetics in synapses by graph-constrained correlation dynamics

Astochastic reaction network model of Ca(2+) dynamics in synapses (Pepke et al PLoS Comput. Biol. 6 e1000675) is expressed and simulated using rule-based reaction modeling notation in dynamical grammars and in MCell. The model tracks the response of calmodulin and CaMKII to calcium influx in synapse...

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Bibliografiske detaljer
Udgivet i:Phys Biol
Main Authors: Johnson, Todd, Bartol, Tom, Sejnowski, Terrence, Mjolsness, Eric
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489159/
https://ncbi.nlm.nih.gov/pubmed/26086598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/12/4/045005
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