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Model reduction for stochastic CaMKII reaction kinetics in synapses by graph-constrained correlation dynamics

Astochastic reaction network model of Ca(2+) dynamics in synapses (Pepke et al PLoS Comput. Biol. 6 e1000675) is expressed and simulated using rule-based reaction modeling notation in dynamical grammars and in MCell. The model tracks the response of calmodulin and CaMKII to calcium influx in synapse...

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Dettagli Bibliografici
Pubblicato in:Phys Biol
Autori principali: Johnson, Todd, Bartol, Tom, Sejnowski, Terrence, Mjolsness, Eric
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489159/
https://ncbi.nlm.nih.gov/pubmed/26086598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/12/4/045005
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