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Photoactivatable CaMKII induces synaptic plasticity in single synapses

Optogenetic approaches for studying neuronal functions have proven their utility in the neurosciences. However, optogenetic tools capable of inducing synaptic plasticity at the level of single synapses have been lacking. Here, we engineered a photoactivatable (pa)CaMKII by fusing a light-sensitive d...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Shibata, Akihiro C. E., Ueda, Hiromi H., Eto, Kei, Onda, Maki, Sato, Aiko, Ohba, Tatsuko, Nabekura, Junichi, Murakoshi, Hideji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854602/
https://ncbi.nlm.nih.gov/pubmed/33531495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21025-6
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