Laddar...
An NSAID-like Compound, FT-9, Preferentially Inhibits γ-Secretase Cleavage of the Amyloid Precursor Protein Compared to Its Effect on Amyloid Precursor-like Protein 1()
Inhibition of γ-secretase cleavage of the amyloid precursor protein (APP) is a prime target for the development of therapeutics for treating Alzheimer’s disease; however, complete inhibition of this activity would also impair the processing of many other proteins, including the APP homologues, amylo...
Sparad:
| I publikationen: | Biochemistry |
|---|---|
| Huvudupphovsmän: | , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2009
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4489158/ https://ncbi.nlm.nih.gov/pubmed/19821615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901237k |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|