Učitavanje...
An NSAID-like Compound, FT-9, Preferentially Inhibits γ-Secretase Cleavage of the Amyloid Precursor Protein Compared to Its Effect on Amyloid Precursor-like Protein 1()
Inhibition of γ-secretase cleavage of the amyloid precursor protein (APP) is a prime target for the development of therapeutics for treating Alzheimer’s disease; however, complete inhibition of this activity would also impair the processing of many other proteins, including the APP homologues, amylo...
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| Izdano u: | Biochemistry |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4489158/ https://ncbi.nlm.nih.gov/pubmed/19821615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901237k |
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