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Microsatellite Instability Use in Mismatch Repair Gene Sequence Variant Classification
Inherited mutations in the DNA mismatch repair genes (MMR) can cause MMR deficiency and increased susceptibility to colorectal and endometrial cancer. Microsatellite instability (MSI) is the defining molecular signature of MMR deficiency. The clinical classification of identified MMR gene sequence v...
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| Publicado no: | Genes (Basel) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4488658/ https://ncbi.nlm.nih.gov/pubmed/25831438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes6020150 |
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