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Microsatellite instability and mismatch repair gene inactivation in sporadic pancreatic and colon tumours
Genomic instability has been proposed as a new mechanism of carcinogenesis involved in hereditary non-polyposis colorectal cancer (HNPCC) and in a large number of sporadic cancers like pancreatic and colon tumours. Mutations in human mismatch repair genes have been found in HNPCC patients, but their...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363009/ https://ncbi.nlm.nih.gov/pubmed/10389971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690314 |
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