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Mismatch repair polymorphisms and risk of colon cancer, tumour microsatellite instability and interactions with lifestyle factors

BACKGROUND: Germline mutations in DNA mismatch repair (MMR) genes cause Lynch syndrome colon cancers. Less understood is the risk of colon cancer associated with common polymorphisms in MMR genes and the potential interacting role of lifestyle factors known to damage DNA. METHODS: A study was conduc...

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Bibliografske podrobnosti
Main Authors: Campbell, P T, Curtin, K, Ulrich, C M, Samowitz, W S, Bigler, J, Velicer, C M, Caan, B, Potter, J D, Slattery, M L
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903215/
https://ncbi.nlm.nih.gov/pubmed/18523027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2007.144220
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