Sulforaphane Reverses the Expression of Various Tumor Suppressor Genes by Targeting DNMT3B and HDAC1 in Human Cervical Cancer Cells

Sulforaphane (SFN) may hinder carcinogenesis by altering epigenetic events in the cells; however, its molecular mechanisms are unclear. The present study investigates the role of SFN in modifying epigenetic events in human cervical cancer cells, HeLa. HeLa cells were treated with SFN (2.5 µM) for a...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Ali Khan, Munawwar, Kedhari Sundaram, Madhumitha, Hamza, Amina, Quraishi, Uzma, Gunasekera, Dian, Ramesh, Laveena, Goala, Payal, Al Alami, Usama, Ansari, Mohammad Zeeshan, Rizvi, Tahir A., Sharma, Chhavi, Hussain, Arif
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487331/
https://ncbi.nlm.nih.gov/pubmed/26161119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/412149
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