HDAC3 regulates DNMT1 expression in multiple myeloma: therapeutic implications

Epigenetic signaling pathways are implicated in tumorigenesis and therefore histone deacetylases (HDACs) represent novel therapeutic targets for cancers including multiple myeloma (MM). Although non-selective HDAC inhibitors show anti-MM activities, unfavorable side effects limit their clinical effi...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Harada, Takeshi, Ohguchi, Hiroto, Grondin, Yohann, Kikuchi, Shohei, Sagawa, Morihiko, Tai, Yu-Tzu, Mazitschek, Ralph, Hideshima, Teru, Anderson, Kenneth C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681897/
https://ncbi.nlm.nih.gov/pubmed/28490812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2017.144
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