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Ribonucleotide reductase large subunit (RRM1) as a novel therapeutic target in multiple myeloma
PURPOSE: To investigate the biologic and clinical significance of ribonucleotide reductase (RR) in multiple myeloma (MM). EXPERIMENTAL DESIGN: We assessed the impact of RR expression on patient outcome in MM. We then characterized the effect of genetic and pharmacological inhibition of RRM1 on MM gr...
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| Publicado no: | Clin Cancer Res |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5581671/ https://ncbi.nlm.nih.gov/pubmed/28442502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-0263 |
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