Ribonucleotide reductase large subunit (RRM1) as a novel therapeutic target in multiple myeloma

PURPOSE: To investigate the biologic and clinical significance of ribonucleotide reductase (RR) in multiple myeloma (MM). EXPERIMENTAL DESIGN: We assessed the impact of RR expression on patient outcome in MM. We then characterized the effect of genetic and pharmacological inhibition of RRM1 on MM gr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Sagawa, Morihiko, Ohguchi, Hiroto, Harada, Takeshi, Samur, Mehmet K., Tai, Yu-Tzu, Munshi, Nikhil C., Kizaki, Masahiro, Hideshima, Teru, Anderson, Kenneth C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581671/
https://ncbi.nlm.nih.gov/pubmed/28442502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-0263
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge