Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase

Citrullination is a post-translational modification of higher organisms that deiminates arginines in proteins and peptides. It occurs in physiological processes but also pathologies such as multiple sclerosis, fibrosis, Alzheimer’s disease and rheumatoid arthritis (RA). The reaction is catalyzed by...

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Publicado no:Sci Rep
Main Authors: Goulas, Theodoros, Mizgalska, Danuta, Garcia-Ferrer, Irene, Kantyka, Tomasz, Guevara, Tibisay, Szmigielski, Borys, Sroka, Aneta, Millán, Claudia, Usón, Isabel, Veillard, Florian, Potempa, Barbara, Mydel, Piotr, Solà, Maria, Potempa, Jan, Gomis-Rüth, F. Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487231/
https://ncbi.nlm.nih.gov/pubmed/26132828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11969
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