Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase

Citrullination is a post-translational modification of higher organisms that deiminates arginines in proteins and peptides. It occurs in physiological processes but also pathologies such as multiple sclerosis, fibrosis, Alzheimer’s disease and rheumatoid arthritis (RA). The reaction is catalyzed by...

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發表在:Sci Rep
Main Authors: Goulas, Theodoros, Mizgalska, Danuta, Garcia-Ferrer, Irene, Kantyka, Tomasz, Guevara, Tibisay, Szmigielski, Borys, Sroka, Aneta, Millán, Claudia, Usón, Isabel, Veillard, Florian, Potempa, Barbara, Mydel, Piotr, Solà, Maria, Potempa, Jan, Gomis-Rüth, F. Xavier
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487231/
https://ncbi.nlm.nih.gov/pubmed/26132828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11969
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