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Structure, function, and inhibition of a genomic/clinical variant of Porphyromonas gingivalis peptidylarginine deiminase

Citrullination is an essential post‐translational modification in which the guanidinium group of protein and peptide arginines is deiminated by peptidylarginine deiminases (PADs). When deregulated, excessive citrullination leads to inflammation as in severe periodontal disease (PD) and rheumatoid ar...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Bereta, Grzegorz, Goulas, Theodoros, Madej, Mariusz, Bielecka, Ewa, Solà, Maria, Potempa, Jan, Xavier Gomis‐Rüth, F.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371208/
https://ncbi.nlm.nih.gov/pubmed/30638292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3571
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