Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy

Autocrine VEGF is necessary for endothelial survival, although the cellular mechanisms supporting this function are unknown. Here, we show that – even after full differentiation and maturation – continuous expression of VEGF by endothelial cells is needed to sustain vascular integrity and cellular v...

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Detaylı Bibliyografya
Yayımlandı:J Cell Sci
Asıl Yazarlar: Domigan, Courtney K., Warren, Carmen M., Antanesian, Vaspour, Happel, Katharina, Ziyad, Safiyyah, Lee, Sunyoung, Krall, Abigail, Duan, Lewei, Torres-Collado, Antoni X., Castellani, Lawrence W., Elashoff, David, Christofk, Heather R., van der Bliek, Alexander M., Potente, Michael, Iruela-Arispe, M. Luisa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487014/
https://ncbi.nlm.nih.gov/pubmed/25956888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.163774
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