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Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors
Vascular endothelial growth factor (VEGF) is a critical mediator of blood vessel formation during development and in pathological conditions. In this study, we demonstrate that VEGF bioavailability is regulated extracellularly by matrix metalloproteinases (MMPs) through intramolecular processing. Sp...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171712/ https://ncbi.nlm.nih.gov/pubmed/15911882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200409115 |
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