A new cellular model to follow Friedreich's ataxia development in a time-resolved way

Friedreich's ataxia (FRDA) is a recessive autosomal ataxia caused by reduced levels of frataxin (FXN), an essential mitochondrial protein that is highly conserved from bacteria to primates. The exact role of frataxin and its primary function remain unclear although this information would be ver...

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Библиографические подробности
Опубликовано в: :Dis Model Mech
Главные авторы: Vannocci, Tommaso, Faggianelli, Nathalie, Zaccagnino, Silvia, della Rosa, Ilaria, Adinolfi, Salvatore, Pastore, Annalisa
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists 2015
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486863/
https://ncbi.nlm.nih.gov/pubmed/26035392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.020545
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