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A new cellular model to follow Friedreich's ataxia development in a time-resolved way

Friedreich's ataxia (FRDA) is a recessive autosomal ataxia caused by reduced levels of frataxin (FXN), an essential mitochondrial protein that is highly conserved from bacteria to primates. The exact role of frataxin and its primary function remain unclear although this information would be ver...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Dis Model Mech
Main Authors: Vannocci, Tommaso, Faggianelli, Nathalie, Zaccagnino, Silvia, della Rosa, Ilaria, Adinolfi, Salvatore, Pastore, Annalisa
פורמט: Artigo
שפה:Inglês
יצא לאור: The Company of Biologists 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486863/
https://ncbi.nlm.nih.gov/pubmed/26035392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.020545
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