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A new cellular model to follow Friedreich's ataxia development in a time-resolved way

Friedreich's ataxia (FRDA) is a recessive autosomal ataxia caused by reduced levels of frataxin (FXN), an essential mitochondrial protein that is highly conserved from bacteria to primates. The exact role of frataxin and its primary function remain unclear although this information would be ver...

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Dettagli Bibliografici
Pubblicato in:Dis Model Mech
Autori principali: Vannocci, Tommaso, Faggianelli, Nathalie, Zaccagnino, Silvia, della Rosa, Ilaria, Adinolfi, Salvatore, Pastore, Annalisa
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486863/
https://ncbi.nlm.nih.gov/pubmed/26035392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.020545
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