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Adding a temporal dimension to the study of Friedreich's ataxia: the effect of frataxin overexpression in a human cell model
The neurodegenerative disease Friedreich's ataxia is caused by lower than normal levels of frataxin, an important protein involved in iron–sulfur (Fe-S) cluster biogenesis. An important step in designing strategies to treat this disease is to understand whether increasing the frataxin levels by...
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| Pubblicato in: | Dis Model Mech |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Company of Biologists Ltd
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6031361/ https://ncbi.nlm.nih.gov/pubmed/29794127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.032706 |
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