Adding a temporal dimension to the study of Friedreich's ataxia: the effect of frataxin overexpression in a human cell model

The neurodegenerative disease Friedreich's ataxia is caused by lower than normal levels of frataxin, an important protein involved in iron–sulfur (Fe-S) cluster biogenesis. An important step in designing strategies to treat this disease is to understand whether increasing the frataxin levels by...

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Bibliografische gegevens
Gepubliceerd in:Dis Model Mech
Hoofdauteurs: Vannocci, Tommaso, Notario Manzano, Roberto, Beccalli, Ombretta, Bettegazzi, Barbara, Grohovaz, Fabio, Cinque, Gianfelice, de Riso, Antonio, Quaroni, Luca, Codazzi, Franca, Pastore, Annalisa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists Ltd 2018
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031361/
https://ncbi.nlm.nih.gov/pubmed/29794127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.032706
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