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An efficient and mild oxidant for the synthesis of s-tetrazines

PhI(OAc)(2) serves as a mild and effective oxidant for the synthesis of s-tetrazine derivatives— molecules of emerging significance to the field of bioorthogonal chemistry. This reagent serves as a complementary oxidant to harsher nitrous reagents. Use of PhI(OAc)(2) improves the synthesis of 5-amin...

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Détails bibliographiques
Publié dans:Tetrahedron Lett
Auteurs principaux: Selvaraj, Ramajeyam, Fox, Joseph M.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486492/
https://ncbi.nlm.nih.gov/pubmed/26146418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2014.07.012
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