Immunomodulatory drugs target IKZF1-IRF4-MYC axis in primary effusion lymphoma in a cereblon-dependent manner and display synergistic cytotoxicity with BRD4 inhibitors

Lignende værker

• Targeting Myc in KSHV-associated primary effusion lymphoma with BET bromodomain inhibitors
  af: Tolani, Bhairavi, et al.
  Udgivet: (2013)
• NEMO Is Essential for Kaposi's Sarcoma-Associated Herpesvirus-Encoded vFLIP K13-Induced Gene Expression and Protection against Death Receptor-Induced Cell Death, and Its N-Terminal 251 Residues Are Sufficient for This Process
  af: Tolani, Bhairavi, et al.
  Udgivet: (2014)
• Narciclasine, an isocarbostyril alkaloid, has preferential activity against primary effusion lymphoma
  af: Gopalakrishnan, Ramakrishnan, et al.
  Udgivet: (2020)
• A purine scaffold HSP90 inhibitor BIIB021 has selective activity against KSHV-associated Primary Effusion Lymphoma and blocks vFLIP K13-induced NF-κB
  af: Gopalakrishnan, Ramakrishnan, et al.
  Udgivet: (2013)
• Kaposi’s Sarcoma Associated Herpesvirus Encoded Viral FLICE Inhibitory Protein K13 Activates NF-κB Pathway Independent of TRAF6, TAK1 and LUBAC
  af: Matta, Hittu, et al.
  Udgivet: (2012)