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CD22ΔE12 as a molecular target for RNAi therapy

B-precursor acute lymphoblastic leukemia (BPL) is the most common form of cancer in children and adolescents. Our recent studies have demonstrated that CD22ΔE12 is a characteristic genetic defect of therapy-refractory clones in pediatric BPL and implicated the CD22ΔE12 genetic defect in the aggressi...

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Bibliographic Details
Published in:Br J Haematol
Main Authors: Uckun, Fatih M., Ma, Hong, Cheng, Jianjun, Myers, Dorothea E., Qazi, Sanjive
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486322/
https://ncbi.nlm.nih.gov/pubmed/25659406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.13306
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