Liposomal Nanoparticles of a Spleen Tyrosine Kinase P-Site Inhibitor Amplify the Potency of Low Dose Total Body Irradiation Against Aggressive B-Precursor Leukemia and Yield Superior Survival Outcomes in Mice()

This study was designed to improve the efficacy of radiation therapy against radiation-resistant leukemia. We report that the potency of low dose radiation therapy against B-precursor acute lymphoblastic leukemia (BPL) can be markedly enhanced by combining radiation with a liposomal nanoparticle (LN...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Uckun, Fatih M., Myers, Dorothea E., Cheng, Jianjun, Qazi, Sanjive
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535154/
https://ncbi.nlm.nih.gov/pubmed/26285772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.04.005
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