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Unlocking truths of γ-secretase in Alzheimer’s disease: what is the translational potential?

Considerable evidence, particularly from genetics, points to the aggregation-prone amyloid β-peptide as a pathogenic entity in Alzheimer’s disease. Hence, the proteases that produce this peptide from its precursor protein have been prime targets for the development of potential therapeutics. One of...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Future Neurol
Yazar: Wolfe, Michael S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486289/
https://ncbi.nlm.nih.gov/pubmed/26146489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fnl.14.35
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