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Probing Mechanisms and Therapeutic Potential of γ-Secretase in Alzheimer’s Disease

The membrane-embedded γ-secretase complex carries out hydrolysis within the lipid bilayer in proteolyzing nearly 150 different membrane protein substrates. Among these substrates, the amyloid precursor protein (APP) has been the most studied, as generation of aggregation-prone amyloid β-protein (Aβ)...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Molecules
Päätekijä: Wolfe, Michael S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828430/
https://ncbi.nlm.nih.gov/pubmed/33450968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26020388
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