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Unlocking truths of γ-secretase in Alzheimer’s disease: what is the translational potential?

Considerable evidence, particularly from genetics, points to the aggregation-prone amyloid β-peptide as a pathogenic entity in Alzheimer’s disease. Hence, the proteases that produce this peptide from its precursor protein have been prime targets for the development of potential therapeutics. One of...

詳細記述

保存先:
書誌詳細
出版年:Future Neurol
第一著者: Wolfe, Michael S
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486289/
https://ncbi.nlm.nih.gov/pubmed/26146489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fnl.14.35
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