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Unlocking truths of γ-secretase in Alzheimer’s disease: what is the translational potential?
Considerable evidence, particularly from genetics, points to the aggregation-prone amyloid β-peptide as a pathogenic entity in Alzheimer’s disease. Hence, the proteases that produce this peptide from its precursor protein have been prime targets for the development of potential therapeutics. One of...
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| Veröffentlicht in: | Future Neurol |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4486289/ https://ncbi.nlm.nih.gov/pubmed/26146489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fnl.14.35 |
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