Prolonged sirolimus administration after allogeneic hematopoietic cell transplantation is associated with decreased risk for moderate-severe chronic graft-versus-host disease

Effective pharmacological strategies employed in allogeneic hematopoietic cell transplantation should prevent serious chronic graft-versus-host disease and facilitate donor-recipient immune tolerance. Based on demonstrated pro-tolerogenic activity, sirolimus (rapamycin) is an agent with promise to a...

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Bibliographic Details
Published in:Haematologica
Main Authors: Pidala, Joseph, Kim, Jongphil, Alsina, Melissa, Ayala, Ernesto, Betts, Brian C., Fernandez, Hugo F., Field, Teresa, Jim, Heather, Kharfan-Dabaja, Mohamed A., Locke, Frederick L., Mishra, Asmita, Nishihori, Taiga, Ochoa-Bayona, Leonel, Perez, Lia, Riches, Marcie, Anasetti, Claudio
Format: Artigo
Language:Inglês
Published: Ferrata Storti Foundation 2015
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486232/
https://ncbi.nlm.nih.gov/pubmed/25840599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.123588
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