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Pharmacokinetic targeting of intravenous busulfan reduces conditioning regimen related toxicity following allogeneic hematopoietic cell transplantation for acute myelogenous leukemia

Optimal conditioning therapy for hematopoietic cell transplantation (HCT) in acute myelogenous leukemia (AML) remains undefined. We retrospectively compared outcomes of a consecutive series of 51 AML patients treated with oral busulfan (1 mg/kg every 6 hours for 4 days) and cyclophosphamide (60 mg/k...

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Detalhes bibliográficos
Main Authors: Pidala, Joseph, Kim, Jongphil, Anasetti, Claudio, Kharfan-Dabaja, Mohamed A, Nishihori, Taiga, Field, Teresa, Perkins, Janelle, Perez, Lia, Fernandez, Hugo F
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958877/
https://ncbi.nlm.nih.gov/pubmed/20925957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-3-36
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