Ofatumumab in Combination with Glucocorticoids for Primary Therapy of Chronic Graft-versus-Host Disease: Phase I Trial Results

Standard primary therapy for chronic graft-versus-host disease (GVHD) is incompletely effective. Based on biologic insights implicating pathogenic B cells, we conducted a phase I trial examining the combination of standard (1 mg/kg/day prednisone) glucocorticoid therapy with ofatumumab, a humanized...

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Detalhes bibliográficos
Publicado no:Biol Blood Marrow Transplant
Principais autores: Pidala, Joseph, Kim, Jongphil, Betts, Brian C., Alsina, Melissa, Ayala, Ernesto, Fernandez, Hugo F., Field, Teresa, Kharfan-Dabaja, Mohamed A., Locke, Frederick L., Mishra, Asmita, Nishihori, Taiga, Ochoa-Bayona, Leonel, Perez, Lia, Riches, Marcie, Anasetti, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757506/
https://ncbi.nlm.nih.gov/pubmed/25805300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2015.03.014
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