Clinical Validation of a Multiplex Kit for RAS Mutations in Colorectal Cancer: Results of the RASKET (RAS KEy Testing) Prospective, Multicenter Study

BACKGROUND: RAS (KRAS and NRAS) testing is required to predict anti-epidermal growth factor receptor (EGFR) treatment efficacy in metastatic colorectal cancer (CRC). Although direct sequencing (DS) with manual microdissection (MMD) is widely used, a diagnostic kit providing rapid detections of RAS m...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Yoshino, Takayuki, Muro, Kei, Yamaguchi, Kensei, Nishina, Tomohiro, Denda, Tadamichi, Kudo, Toshihiro, Okamoto, Wataru, Taniguchi, Hiroya, Akagi, Kiwamu, Kajiwara, Takeshi, Hironaka, Shuichi, Satoh, Taroh
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486202/
https://ncbi.nlm.nih.gov/pubmed/26137573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.02.007
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