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Targeted therapy in melanoma – the role of BRAF, RAS and KIT mutations

Melanoma today is considered as a spectrum of melanocytic malignancies characterised by clinical and molecular features, including targetable mutations in several kinases such as BRAF or c-KIT. The successful development of therapies targeting these mutations has resulted in new specific treatment o...

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Detalhes bibliográficos
Main Authors: Goldinger, Simone M., Murer, Carla, Stieger, Pascale, Dummer, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041182/
https://ncbi.nlm.nih.gov/pubmed/26217117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejcsup.2013.07.011
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