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Molecular Targeted Approaches for Advanced BRAF V600, N-RAS, c-KIT, and GNAQ Melanomas

The introduction of a newly developed target therapy for metastatic melanomas poses the challenge to have a good molecular stratification of those patients who may benefit from this therapeutic option. Practically, BRAF mutation status (V600E) is commonly screened although other non-V600E mutations...

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Détails bibliographiques
Auteurs principaux: Giovanni, Ponti, Giovanni, Pellacani, Aldo, Tomasi, Pietro, Loschi, Gabriele, Luppi, Fabio, Gelsomino, Caterina, Longo
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925612/
https://ncbi.nlm.nih.gov/pubmed/24591764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/671283
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