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Development of encorafenib for BRAF-mutated advanced melanoma

PURPOSE OF REVIEW: To describe the pharmacological properties, preclinical and clinical data of the novel V-Raf Murine Sarcoma Viral Oncogene Homolog B (BRAF)-inhibitor encorafenib (LGX818) and to compare these with established BRAF-inhibitors in the treatment of locally advanced or metastatic melan...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Curr Opin Oncol
Egile Nagusiak: Koelblinger, Peter, Thuerigen, Olaf, Dummer, Reinhard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Lippincott Williams & Wilkins 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815646/
https://ncbi.nlm.nih.gov/pubmed/29356698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0000000000000426
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