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Development of encorafenib for BRAF-mutated advanced melanoma
PURPOSE OF REVIEW: To describe the pharmacological properties, preclinical and clinical data of the novel V-Raf Murine Sarcoma Viral Oncogene Homolog B (BRAF)-inhibitor encorafenib (LGX818) and to compare these with established BRAF-inhibitors in the treatment of locally advanced or metastatic melan...
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| Veröffentlicht in: | Curr Opin Oncol |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Lippincott Williams & Wilkins
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5815646/ https://ncbi.nlm.nih.gov/pubmed/29356698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0000000000000426 |
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