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Ire1 Has Distinct Catalytic Mechanisms for XBP1/HAC1 Splicing and RIDD
An evolutionarily conserved unfolded protein response (UPR) component, IRE1, cleaves XBP1/HAC1 introns in order to generate spliced mRNAs that are translated into potent transcription factors. IRE1 also cleaves endoplasmic-reticulum-associated RNAs leading to their decay, an activity termed regulate...
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| Publicado en: | Cell Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4486022/ https://ncbi.nlm.nih.gov/pubmed/25437541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.09.016 |
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