Altered Interactions between the Gut Microbiome and Colonic Mucosa Precede Polyposis in APC(Min/+) Mice

Mutation of the adenomatous polyposis coli (APC gene), an early event in the adenoma-carcinoma sequence, is present in 70-80% of sporadic human colorectal adenomas and carcinomas. To test the hypothesis that mutation of the APC gene alters microbial interactions with host intestinal mucosa prior to...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Son, Joshua S., Khair, Shanawaj, Pettet, Donald W., Ouyang, Nengtai, Tian, Xinyu, Zhang, Yuanhao, Zhu, Wei, Mackenzie, Gerardo G., Robertson, Charles E., Ir, Diana, Frank, Daniel N., Rigas, Basil, Li, Ellen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485894/
https://ncbi.nlm.nih.gov/pubmed/26121046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127985
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