Altered Interactions between the Gut Microbiome and Colonic Mucosa Precede Polyposis in APC(Min/+) Mice

Mutation of the adenomatous polyposis coli (APC gene), an early event in the adenoma-carcinoma sequence, is present in 70-80% of sporadic human colorectal adenomas and carcinomas. To test the hypothesis that mutation of the APC gene alters microbial interactions with host intestinal mucosa prior to...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Son, Joshua S., Khair, Shanawaj, Pettet, Donald W., Ouyang, Nengtai, Tian, Xinyu, Zhang, Yuanhao, Zhu, Wei, Mackenzie, Gerardo G., Robertson, Charles E., Ir, Diana, Frank, Daniel N., Rigas, Basil, Li, Ellen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485894/
https://ncbi.nlm.nih.gov/pubmed/26121046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127985
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