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IL-10 enhances CTL-mediated tumor rejection by inhibiting highly suppressive CD4(+) T cells and promoting CTL persistence in a murine model of plasmacytoma
Interleukin-10 (IL-10) is a potent anti-inflammatory cytokine that regulates immune responses. IL-10 has also been shown to enhance antitumor CD8(+) T-cell responses in tumor models although the underlying mechanisms are not fully understood. In this study, we used a series of genetic mouse models a...
שמור ב:
| הוצא לאור ב: | Oncoimmunology |
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| Main Authors: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Taylor & Francis
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485799/ https://ncbi.nlm.nih.gov/pubmed/26140236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1014232 |
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