IL-10 enhances CTL-mediated tumor rejection by inhibiting highly suppressive CD4(+) T cells and promoting CTL persistence in a murine model of plasmacytoma

Interleukin-10 (IL-10) is a potent anti-inflammatory cytokine that regulates immune responses. IL-10 has also been shown to enhance antitumor CD8(+) T-cell responses in tumor models although the underlying mechanisms are not fully understood. In this study, we used a series of genetic mouse models a...

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Bibliografiska uppgifter
I publikationen:Oncoimmunology
Huvudupphovsmän: Wang, Lixin, Liu, Jin-Qing, Talebian, Fatemeh, Liu, Zhenzhen, Yu, Li, Bai, Xue-Feng
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2015
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485799/
https://ncbi.nlm.nih.gov/pubmed/26140236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1014232
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