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IL-10 Contributes to the Suppressive Function of Tumor Associated Myeloid Cells and Enhances Myeloid Cell Accumulation in Tumors

Studies have revealed that tumor associated myeloid cells (TAMC) are one of the major sources of IL-10 in tumor-bearing mice. However, the significance of TAMC-derived IL-10 in tumor immunity is poorly understood. Here we show that IL-10 blockade or IL-10-deficiency reduces the capacity of TAMC in s...

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Bibliografiske detaljer
Main Authors: Wang, Li-Xin, Talebian, Fatemeh, Liu, Jin-Qing, Khattabi, Mazin, Yu, Li, Bai, Xue-Feng
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279616/
https://ncbi.nlm.nih.gov/pubmed/22050574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-3083.2011.02662.x
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