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IL-10 Contributes to the Suppressive Function of Tumor Associated Myeloid Cells and Enhances Myeloid Cell Accumulation in Tumors
Studies have revealed that tumor associated myeloid cells (TAMC) are one of the major sources of IL-10 in tumor-bearing mice. However, the significance of TAMC-derived IL-10 in tumor immunity is poorly understood. Here we show that IL-10 blockade or IL-10-deficiency reduces the capacity of TAMC in s...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3279616/ https://ncbi.nlm.nih.gov/pubmed/22050574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-3083.2011.02662.x |
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