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Tumor-derived IL-35 promotes tumor growth by enhancing myeloid cell accumulation and angiogenesis
IL-35 is a member of the IL-12 family of cytokines consisting of IL-12 p35 subunit and IL-12 p40-related protein subunit, EBV-induced gene 3 (EBI3). IL-35 functions through IL-35R and has a potent immune suppressive activity. Although IL-35 has been demonstrated to be produced by regulatory T cells,...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3578001/ https://ncbi.nlm.nih.gov/pubmed/23345334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202535 |
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