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Time to Akt: Superior tumor-reactive T cells for adoptive immunotherapy

T cells are crucial players in the protection against cancer, and can be used in adoptive cell therapy to prevent or treat relapse. However, their state of differentiation determines their effectiveness, with early memory cells being the most favorable. Here, we discuss restraining of differentiatio...

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Publicat a:Oncoimmunology
Autors principals: van der Waart, Anniek B, Hobo, Willemijn, Dolstra, Harry
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485741/
https://ncbi.nlm.nih.gov/pubmed/26155398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2014.1003016
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