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Immune checkpoint blockade in microsatellite instable colorectal cancers: Back to the clinic

The active Th1/CTL immune microenvironment of Microsatellite Instable colorectal cancer (CRC) is counterbalanced by up-regulated expression of multiple immune checkpoints, suggesting that defective mismatch repair may be a biomarker to select CRC patients for treatment with checkpoint inhibitors. Th...

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Detaylı Bibliyografya
Yayımlandı:Oncoimmunology
Asıl Yazarlar: Housseau, Franck, Llosa, Nicolas J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485714/
https://ncbi.nlm.nih.gov/pubmed/26155426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1008858
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