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Immune checkpoint blockade in microsatellite instable colorectal cancers: Back to the clinic
The active Th1/CTL immune microenvironment of Microsatellite Instable colorectal cancer (CRC) is counterbalanced by up-regulated expression of multiple immune checkpoints, suggesting that defective mismatch repair may be a biomarker to select CRC patients for treatment with checkpoint inhibitors. Th...
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| Pubblicato in: | Oncoimmunology |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485714/ https://ncbi.nlm.nih.gov/pubmed/26155426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1008858 |
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