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Incorporating Individual and Collective Ethics into Phase I Cancer Trial Designs

A general framework is proposed for Bayesian model based designs of Phase I cancer trials, in which a general criterion for coherence of a design is also developed. This framework can incorporate both “individual” and “collective” ethics into the design of the trial. We propose a new design that min...

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書目詳細資料
發表在:Biometrics
Main Authors: Bartroff, Jay, Lai, Tze Leung
格式: Artigo
語言:Inglês
出版: 2010
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485382/
https://ncbi.nlm.nih.gov/pubmed/20731643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1541-0420.2010.01471.x
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