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Titania-Catalyzed Radiofluorination of Tosylated Precursors in Highly Aqueous Media

Nucleophilic radiofluorination is an efficient synthetic route to many positron-emission tomography (PET) probes, but removal of water to activate the cyclotron-produced [(18)F]fluoride has to be performed prior to reaction, which significantly increases overall radiolabeling time and causes radioac...

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Detalles Bibliográficos
Publicado en:J Am Chem Soc
Main Authors: Sergeev, Maxim E., Morgia, Federica, Lazari, Mark, Wang, Christopher, van Dam, R. Michael
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485375/
https://ncbi.nlm.nih.gov/pubmed/25860121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b02659
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