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Titania-Catalyzed Radiofluorination of Tosylated Precursors in Highly Aqueous Media
Nucleophilic radiofluorination is an efficient synthetic route to many positron-emission tomography (PET) probes, but removal of water to activate the cyclotron-produced [(18)F]fluoride has to be performed prior to reaction, which significantly increases overall radiolabeling time and causes radioac...
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| Veröffentlicht in: | J Am Chem Soc |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485375/ https://ncbi.nlm.nih.gov/pubmed/25860121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b02659 |
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