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Syntheses of mGluR5 PET Radioligands through the Radiofluorination of Diaryliodonium Tosylates
3-Fluoro-1-((thiazol-4-yl)ethynyl)benzenes constitute an important class of high-affinity metabotropic glutamate subtype 5 receptor (mGluR5) ligands, some of which have been labeled with fluorine-18 (t(1/2) = 109.7 min), to provide radioligands for molecular imaging of brain mGluR5 in living animal...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3186059/ https://ncbi.nlm.nih.gov/pubmed/21845279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1ob05555k |
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